Program

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09:00-10:15

ISCVID Council

Room 14

10:30-12:30

Duke Criteria for IE Working Group

Auditorium

D. Durack (USA), V. Fowler (USA) and J.M. Miro (Spain)

12:30-13:30

Pack Lunch

Cloister and first floor hall

13:30-14:00

Welcome Address

Auditorium

Dr. JM Campistol, Director Hospital Clinic of Barcelona

Dr. A. Trilla, Dean Faculty of Medicine, University of Barcelona

Dr. E. Quintana, Vicepresident of ISCVD Symposium

Dr. JM Miro, ISCVID President

14:00-16:00

Session I: Evolving epidemiology of infective endocarditis

Auditorium

Moderators: M. Martínez-Selles (Spain) and P. Moreillon (Switzerland)

14:00-14:20	IE trends and injection drug use. L.M. Baddour (USA)
14:20-14:40	TAVI endocarditis: A new and growing clinical entity with surgical challenges. A. Regueiro (Spain)
14:40-15:00	The hidden face of IE: clinical characteristics and prognosis of IE in community centers. O. Gasch (Spain)
15:00-15:30	Discussion
15:30-15-45	Oral presentation-1 O-01 Infective endocarditis on MitraClip: a systematic literature review L. Bertolino, F. Patauner, R. Gallo, M. Said Ramadan, E. Durante Mangoni. Università degli studi della Campania "L. Vanvitelli", AORN Ospedali dei Colli - Monaldi Hospital - Napoli, Italy.
15:45-16:00	Oral presentation-2 O-02 Staphylococcus aureus bacteremia, Cardiovascular implantable electronic device and the risk of CIED infection, endocarditis, pocket infection, and relapse C. Carlsen¹, A. Petropoulos¹, F. Gadler², M. Rasmussen³, A. Berge¹. ¹Department of Infectious Diseases, Stockholm, Sweden; ²Karolinska Institute, Stockholm, Sweden; ³Department of Infectious Diseases, Lund, Sweden.

16:00-16:30

Coffee & Poster visit

Hall third floor

16:30-18:30

Session II: Experimental and clinical pathogenesis

Auditorium

Moderators: C. Garcia-de-la-Maria (Spain) and D. Durack (USA)

16:30-16:50	Impact of antibiotic treatment on the size of the vegetations in the animal model. A. Dahl (Denmark)
16:50-17:10	Novel phage lysins for treating staphylococcal endocardits: from bench to bedside. A. Bayer (USA)
17:10-17:30	Colonic neoplasms and S. gallolyticus and E. faecalis endocarditis. J.M. Pericas (Spain)
17:30-18:00	Discussion
18:00-18-15	Oral presentation-3 O-03 TARGETED PROTEOMIC ANALYSIS REVEALS ASSOCIATIONS BETWEEN SPECIFIC BACTERIAL VIRULENCE FACTORS AND SEVERITY IN STAPHYLOCOCCUS AUREUS BACTEREMIA C. Bouchiat¹, S. Bastien¹, I. Macavei², N. Mouton², J.P. Rasigade¹, F. Vincent¹, X. Duval³, V. Le Moing⁴, K. Moreau¹, J. Lemoine², F. Vandenesch¹. ¹CIRI, Centre International de Recherche en Infectiologie, Université de Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France; ²Institut des Sciences Analytiques, UMR 5280, villeurbanne, France; ³University Hospital Bichat, paris, France; ⁴CHU de Montpellier, Montpellier, France.
18:15-18:30	Oral presentation-4 O-04 Biofilms in endocarditis: is there a therapeutic consequence? Put up for discussion J. Kikhney¹, A. Moter². ¹Charité-Universitätsmedizin Berlin, Institute of Microbiology, Infectious Diseases and Immunology, MoKi Analytics, Berlin, Germany; ²Charité-Universitätsmedizin Berlin, Institute of Microbiology, Infectious Diseases and Immunology, Moter Diagnostics, MoKi Analytics, Berlin, Germany.

18:30-19:30

Meet-to-party with a glass of wine/cava

Cloister and first floor hall

20:00-22:00

Dinner for Speakers, chairs and ISCVID council members

TBD

08:30-10:30

Session III: Prevention of cardiovascular infections

Auditorium

Moderators: J.M. Tolosana (Spain) and J.T.M. van der Meer (Netherlands)

08:30-08:50	When will we have a clinical trial to clarify our doubts? B. Hoen (France)
08:50-09:10	Preventing infective endocarditis: How much does oral hygiene matter? P. Lockhart (USA)
09:10-09:30	Where are we now with antibiotic prevention of infective endocarditis? M.H. Thornhill (UK)
09:30-09:50	Is antimicrobial prophylaxis different for TAVI and CIED? Usefulness of antibacterial envelopes. A. Conen (Switzerland)
09:50:10:15	Discussion
10:15-10:30	Oral presentation-5 O-05 Efficacy and safety of mechanical thrombectomy in infective endocarditis-related large-vessel occlusion strokes: A systematic review of 87 cases. P. Lapeña¹, X. Urra¹, J. Llopis¹, G. Cuervo¹, M. Hernández-Meneses¹, O. Maisterra², F. Escrihuela³, M.L. Pedro-Botet⁴, N. Benito⁵, C. Sáez⁶, C. Olmos⁷, F. Hernández-Fernández⁸, B. Vidal¹, E. Sandoval¹, C. Falces¹, E. Quintana¹, A. Moreno¹, J.M. Miró¹. ¹Hospital Clínic de Barcelona, Barcelona, Spain; ²Hospital Universitari Vall d´Hebrón, Barcelona, Spain; ³Hospital Universitari de Bellvitge, L´Hospitalet de Llobregat, Spain; ⁴Hospital Universitari Germans Trias i Pujol, Badalona, Spain; ⁵Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; ⁶Hospital Universitario de La Princesa, Madrid, Spain; ⁷Hospital Clínico San Carlos, Madrid, Spain; ⁸Complejo Hospitalario Universitario de Albacete, Albacete, Spain.

10:30:11:00

Coffee & Poster visit

Hall third floor

11:00-13:00

Session IV: Diagnosis of infective endocarditis

Auditorium

Moderators: A. Perissinotti (Spain) and A.W. Karchmer (USA)

11:00-11:20	Improving microbiological diagnosis: molecular biology and cell-free DNA. C. Petti (USA)
11:20-11:40	New imaging tools: MRI, PET/TC, leukocyte scintigraphy. M. Pizzi (Spain)
11:40-12:00	What is the current role of echo? E.L. Fosbol (Denmark)
12:00-12:15	Discussion
12:15-13:00	ISCVID Initiative to update the Duke criteria D. Durack (USA): Introduction V. Fowler (USA), Chair, ISCVID task force: Report on progress Feedback and suggestions from the audience moderated by D. Durack (USA) and V. Fowler (USA)

13:00-14:00

Pack Lunch

Cloister and first floor hall

14:00-16:00

Session V: How to improve the management of infective endocarditis

Auditorium

Moderators: J. Vila (Spain) and C. Selton-Suty (France)

14:00-14:20	How to develop and improve endocarditis teams? V. Delgado (Netherlands)
14:20-14:40	Scores predicting endocarditis in Gram-Positive bacteremia, V. le Moing (France)
14:40-15:00	Scores, scores and more scores for cardiac surgey … Do they help us? B. Iung (France)
15:00-15:30	Discussion
15:30-15:45	Oral presentation-6 O-06 The LAUsanne STAPHylococcus aureus ENdocarditis (LAUSTAPHEN) score: a prediction score to estimate initial patient risk for infective endocarditis in patients with S. aureus bacteremia M. Papadimitriou-Olivgeris, P. Monney, L. Mueller, L. Senn, B. Guery. Lausanne University Hospital, Lausanne, Switzerland.
15:45-16:00	Oral presentation-7 O-07 Clinical and echocardiographic predictors of embolism in infective endocarditis. M. Papadimitriou-Olivgeris, P. Monney, M. Kirsch, B. Guery. Lausanne University Hospital, Lausanne, Switzerland.

16:00-16:30

Coffee & Poster visit

Hall third floor

16:30-18:30

Session VI: Challenging clinical cases (all lectures based on clinical cases with questions for the panel and audience)

Auditorium

Moderators: M. Hernández-Meneses (Spain) and E. Durante-Mangoni (Italy)

Discuss of the clinical cases: L. M. Baddour (USA), C. Fortes (Brazil), E. Sandoval (Spain), J. Ambrosioni (Spain) and G. Mestres (Spain)

16:30-16:54	Role of thrombectomy for ischemic stroke during IE. X. Urra (Spain)
16:54-17:18	Treating MDR Gram positive IE. P. Tattevin (France)
17:18-17:42	Management of prosthetic vascular graft infections. B. Hasse (Switzerland).
17:42-18:06	Fungal endocarditis. M. Hannan (Ireland)
18:06-18:30	CIED-associated IE. D.C. DeSimone (USA)

18:30-19:00

Special ISCVID lecture: the future of staphylococcal endocarditis. From biofilm eradication to artificial intelligence

Auditorium

Moderators: M. Pujol (Spain) and A. W. Karchmer (USA)

Speaker: V. Fowler (USA)

08:00-10:00

Session VII: Advances in surgical management

Auditorium

Moderators: C. Mestres (Spain) and M. Borger (Germany)

08:00-08:20	Optimal timing for cardicac surgery after hemorragic stroke during IE. T. Doenst (Germany)
08:20-08:40	Challenging aspects of cardiac surgery: from valve repair to Commando procedure. E. Quintana (Spain)
08:40-09:00	Experience with percutaneus removal of right-sided vegetations (IDU, CIED). C. T. Starck (Germany)
09:00-09:30	Discussion
09:30-09:45	Oral presentation-8 O-08 Infective endocarditis and cardiovascular outcomes after transcatheter and surgical aortic valve replacement: a population-based cohort study P. Martin, K. Alexander, C. Anna. Kantonsspital Aarau, Aarau, Switzerland.
09:45-10:00	Oral presentation-9 O-09 Postoperative fever after elective cardiac surgery: a retrospective study I. Zwartkruis, S. Keijmel, J. Jongenotter, G. Geuzebroek, I. Kouijzer. Radboudumc, Nijmegen, Netherlands.

10:00:10:30

Coffee & Poster visit

Hall third floor

10:30-12:30

Session VIII: Changing the paradigm of antimicrobial treatment

Auditorium

Moderators: J.M. Miro (Spain) and V. Chu (USA)

10:30-10:50	Treat early, treat hard! Role of new bactericidal antibiotic combinations. E. Durante-Mangoni (Italy)
10:50-11:10	Switching to OPAT. New GAMES criteria and role of long-acting lipoglycopeptides. M. Kestler
11:10-12:15	Switching to oral therapy.
11:10-11:30	Pros: Experience from Scandinavian countries. M. Rasmussen (Sweden)
11:30-11:50	Cons: What is being done outside the Scandinavian countries? E. Athan (Australia)
11:50-12:15	Feedback and suggestions from the audience moderated together with A.W. Karchmer (USA) and J.T.M. van der Meer (Netherlands)
12:15-12:30	Oral presentation-10 O-10 Long term suppressive antibiotic therapy in infective endocarditis: an observational study A.L. Beaumont, F. Mestre, S. Decaux, C. Bertin, X. Duval, B. Iung, F. Rouzet, M. Para, N. Grall, M. Thy, L. Deconinck. AP-HP, Paris, AP-HP, France.

12:30-13:00

Final session IX: Best papers on cardiovascular infections (2019-22). In memoriam J. Galvez (Spain)

Auditorium

Moderators: A. Moreno (Spain) and M. Hannan (Ireland)

Speaker: G. L. Cuervo (Spain)

13:00-13:30

Closing Ceremony and Awards

Auditorium

Elias Abrutyn Award delivered by Dr A.W. Karchmer (3 min.introduction Dr. Abrutyn)

Ethan Rubinstein Award delivered by Dr D. Durack (3 min.introduction Dr. Rubinstein)

Dr. M. Rasmussen, President of the 2024 ISCVID Symposium, Malmö (Sweden)

Dr. E. Quintana ISCVID Symposium Vicepresident

Dr. JM Miro ISCVID President

13:30-14:30

Closing

Auditorium

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